Yorkville is a village in Belmont and Jefferson counties in the U.S. state of Ohio. The population was 1,079 at the 2010 census.Yorkville lies within two Metropolitan Statistical Areas; the Belmont County portion is part of the Wheeling, WV-OH Metropolitan Statistical Area, while the Jefferson County portion of the village is part of the Weirton-Steubenville, WV-OH Metropolitan Statistical Area.